4-AZIDOBENZOIC ACID
p-Azidobenzoic Acid
CAS: 6427-66-3
Molecular Formula: C7H5N3O2
4-AZIDOBENZOIC ACID - Names and Identifiers
| Name | p-Azidobenzoic Acid |
| Synonyms | AKOS 90315 Azidobenzoicacid TIMTEC-BB SBB008205 p-Azidobenzoic Acid 4-AZIDOBENZOIC ACID P-AZIDOBENZOIC ACID 4-Azidobenzoic acid Azidobenzoic acid,4- Benzoic acid, 4-azido- (4-CARBOXYPHENYL)IMINO-IMINO-AZANIUM 1-(4-carboxyphenyl)triaza-1,2-dien-2-ium |
| CAS | 6427-66-3 |
| EINECS | 229-198-9 |
| InChI | InChI=1/C7H5N3O2/c8-10-9-6-3-1-5(2-4-6)7(11)12/h1-4,8H/p+1 |
4-AZIDOBENZOIC ACID - Physico-chemical Properties
| Molecular Formula | C7H5N3O2 |
| Molar Mass | 163.13 |
| Melting Point | 180 °C(Solv: water (7732-18-5)) |
| Flash Point | -33℃ |
| Solubility | soluble in Methanol |
| Appearance | powder to crystal |
| Color | White to Light red to Green |
| BRN | 1950876 |
| Storage Condition | 2-8°C |
4-AZIDOBENZOIC ACID - Risk and Safety
| Risk Codes | R5 - Heating may cause an explosion R36/37/38 - Irritating to eyes, respiratory system and skin. R48/20/21/22 - R38 - Irritating to the skin R11 - Highly Flammable |
| Safety Description | S15 - Keep away from heat. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S16 - Keep away from sources of ignition. |
| UN IDs | 1479 |
| WGK Germany | 3 |
| HS Code | 29299090 |
| Hazard Class | 4.1 |
| Packing Group | III |
4-AZIDOBENZOIC ACID - Introduction
p-Azidobenzoic (p-Azidobenzoic Acid) is an organic compound with the chemical formula C7H5N3O2. It has the following properties:
Nature:
-Appearance: Colorless crystal or white crystalline powder
-Melting point: about 185-187°C
-Boiling point: about 324°C
-Solubility: Soluble in some organic solvents, such as alcohols and ethers, slightly soluble in water
Use:
-Biochemical research: As a chemical marker, it can be used for radioactive and fluorescent labeling of proteins and nucleic acids
-Chemical synthesis: can be used for organic synthesis reactions, such as nitrogen reaction and coupling reaction
-Pharmaceutical research: May play a key role in the synthesis of specific drugs
Preparation Method:
p-Azidobenzoic Acid can be prepared by reacting benzoic acid with nitrous ammonia under alkaline conditions. There are many specific preparation methods, one of which is to react benzoic acid and sodium nitrite in the presence of concentrated alkali (such as sodium hydroxide) to obtain the intermediate product 4-nitrosobenzoic acid, and then further react with sodium hydroxide and ammonia exchange to obtain the final product p-Azidobenzoic Acid.
Safety Information:
- p-Azidobenzoic Acid is a harmful substance, care should be taken to avoid skin contact and inhalation. Wear appropriate personal protective equipment during operation.
-When using, it should be carried out in strict accordance with the laboratory safety operation procedures, and operate in a well-ventilated place.
-This compound is a possible allergenic substance, which may cause allergic reactions in some people, so special attention should be paid when using it.
Please note that this article only provides general information, and the specific use and operation should be carried out according to the specific situation and experimental requirements.
Nature:
-Appearance: Colorless crystal or white crystalline powder
-Melting point: about 185-187°C
-Boiling point: about 324°C
-Solubility: Soluble in some organic solvents, such as alcohols and ethers, slightly soluble in water
Use:
-Biochemical research: As a chemical marker, it can be used for radioactive and fluorescent labeling of proteins and nucleic acids
-Chemical synthesis: can be used for organic synthesis reactions, such as nitrogen reaction and coupling reaction
-Pharmaceutical research: May play a key role in the synthesis of specific drugs
Preparation Method:
p-Azidobenzoic Acid can be prepared by reacting benzoic acid with nitrous ammonia under alkaline conditions. There are many specific preparation methods, one of which is to react benzoic acid and sodium nitrite in the presence of concentrated alkali (such as sodium hydroxide) to obtain the intermediate product 4-nitrosobenzoic acid, and then further react with sodium hydroxide and ammonia exchange to obtain the final product p-Azidobenzoic Acid.
Safety Information:
- p-Azidobenzoic Acid is a harmful substance, care should be taken to avoid skin contact and inhalation. Wear appropriate personal protective equipment during operation.
-When using, it should be carried out in strict accordance with the laboratory safety operation procedures, and operate in a well-ventilated place.
-This compound is a possible allergenic substance, which may cause allergic reactions in some people, so special attention should be paid when using it.
Please note that this article only provides general information, and the specific use and operation should be carried out according to the specific situation and experimental requirements.
Last Update：2024-04-09 20:49:11
